New top story from Time: We Need More Data in the Fight Against Cancer. Here’s a Plan to Help Us Get There

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For the first time in over a year, we are starting to see a light at the end of the tunnel from the devastation caused by COVID-19. While much work remains to end and avoid a resurgence of the pandemic, public and private investments in scientific research will get us to a new normal. The speed to develop, test and manufacture COVID-19 vaccines has shown how science and technology, supported by leadership from governments and the private sector, have the ability to save lives. For example, the CDC’s V-safe program, which recorded side effects, led to the collection of data from tens of millions of people after vaccination, creating a new paradigm for data collection after drug approval.

These successes show just how much can be done when we invest in science and the systems to deploy it effectively. That is why we believe President Biden has the opportunity to lead on another major investment in scientific leadership: the battle to end suffering from cancer.

Despite recent advancements in medicine, cancer still kills more Americans each year than the COVID-19 pandemic has to date. Significant disparities exist, with African-American men having the highest death rates from cancer of any group in the country.

Now in its fifth of seven years, the Cancer Moonshot program, launched under the leadership of then Vice President Biden, has made significant progress. But with challenges remaining, there is a need to renew commitment, refresh priorities and increase funding for Cancer Moonshot 2.0. These efforts will complement and accelerate the National Cancer Institute’s (NCI) existing work.

We see several interrelated priorities for a second Cancer Moonshot, which can unlock new and needed progress in the war on cancer. To begin: standardizing and collecting cancer-patient data (using the same vocabulary to describe medical events and collecting patient data in the same way so they can be compared), especially on outcomes that matter to patients. Patients want to be part of the solution and participate, through use of their privacy-protected data. For too long, electronic health records have been health system–centric, making it difficult for patients, doctors and researchers to track an individual patient’s data over time and across systems. With standardized, patient-centric data, artificial intelligence (AI) can help identify measures for intercepting cancer early, reducing disparities in outcomes and using precision medicine to get treatments to patients who will most benefit from them. With standardized data, we can also create a national cancer data (NatCanDa) repository that researchers can use to inform treatment development, and better pool and share our data with the world. Data holds the clues to better treating cancer.

In addition, we have to modernize systems at the NCI, the FDA, Centers for Medicare and Medicaid Services and other government agencies that collect cancer-related data. Modernized systems, including outcomes, clinical-trial and claims data, will allow us to use real-world evidence to determine which treatments work best for which types of patients and under which models of care, and the most cost-effective ways of delivering those treatments. This will also serve as the foundation of a coordinated cancer clinical trial infrastructure to support faster and more effective drug development.

Together, these initiatives can set up a national “learning health system” for cancer treatment and prevention, where research informs clinical care, and clinical care informs research. Better data sharing and use of real-world evidence can lay the foundation for similar progress on other diseases, especially complex chronic conditions like heart disease and diabetes.

The ability of science to respond to the COVID-19 pandemic shows that, with the right government, scientific, health care, technology and community leadership, we can come together to save lives.

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New top story from Time: All 53 People Aboard Indonesia Submarine Declared Dead After Vessel’s Wreckage Found

https://ift.tt/3ezrzg5 ANYUWANGI, Indonesia — Indonesia’s military on Sunday officially said all 53 crew members from a submarine that sank and broke apart last week are dead, and that search teams had located the vessel’s wreckage on the ocean floor. The grim announcement comes a day after Indonesia said the submarine was considered sunk, not merely missing , but did not explicitly say whether the crew was dead. Officials had also said the KRI Nanggala 402’s oxygen supply would have run out early Saturday, three days after vessel went missing off the resort island of Bali. “We received underwater pictures that are confirmed as the parts of the submarine, including its rear vertical rudder, anchors, outer pressure body, embossed dive rudder and other ship parts,” military chief Hadi Tjahjanto told reporters in Bali on Sunday. “With this authentic evidence, we can declare that KRI Nanggala 402 has sunk and all the crew members are dead,” Tjahjanto said. An underwater ro...

New top story from Time: ‘One Slip of the Tongue Could Ruin Things.’ Bipartisan Talks on Police Reform Advance—Delicately

https://ift.tt/2ScOdmJ A small bipartisan group of lawmakers in Washington are making an urgent push to get a police reform bill passed in Congress in the wake of a Minneapolis jury finding Derek Chauvin, a white former police officer, guilty of murdering George Floyd, a Black man, last May. Lawmakers on both sides of the aisle say they are optimistic that renewed bipartisan talks will result in a deal that can pass both of the closely split chambers of Congress. President Joe Biden has given lawmakers a deadline to get it done by the anniversary of Floyd’s death on May 25. “Congress should act,” said Biden during his joint address on Wednesday. “We have a giant opportunity to bend the arc of the moral universe toward justice.” The way forward in reforming America’s police force must now be found in a legislative body regularly paralyzed by partisanship and disagreement, on an issue that has become so divisive that compromise can translate to losing support from member...

New top story from Time: 11 Moments From Asian American History That You Should Know

https://ift.tt/330kaRq More than 30 years after President George H.W. Bush signed a law that designated May 1990 as the first Asian American and Pacific Islander Heritage Month , much of Asian American history remains unknown to many Americans—including many Asian Americans themselves. Often the Asian-American history taught in classrooms is limited to a few milestones like the Chinese Exclusion Act of 1882 and the incarceration of people of Japanese descent during World War II, and that abridged version rarely includes the nearly 50 other ethnic groups that make up the fastest-growing racial and ethnic group in the U.S. in the first two decades of the 21st century . To many, the resulting lack of awareness was highlighted after the March 16 Atlanta spa shootings that left six women of Asian descent dead. The killings fit into a larger trend of violence against Asians failing to be seen or charged as a hate crime , even as leaders lamented that “racist attacks [are]… no...

New top story from Time: Why It’s Crucial to Talk to Kids About Gender Pronouns

https://ift.tt/3fKr8kO It’s only been a week since Katherine Locke’s newest book was published, and they’ve already received messages from parents of trans and nonbinary children saying how much it spoke to them. The book, What Are Your Words? , tells the story of a kid named Ari, who is gender fluid and nonbinary and tries out different pronouns depending on how they feel on different days. Aimed at readers aged 4 to 8, the book follows Ari and his nonbinary uncle Lior as they try to figure out what words fit them. “I certainly didn’t grow up talking about pronouns that weren’t she/her, he/him, and I didn’t know how to have these conversations either,” says Locke, who released their first picture book last November and has previously written novels for young adults and adults. “It’s been really gratifying to see people embrace the book and its concepts.” [time-brightcove not-tgx=”true”] With colorful illustrations by Anne Passchier, the book emphasizes that pronouns are...

New top story from Time: ‘What Will Happen When the World Looks Away?’ An Afghan Teacher on How the World Can Protect Girls From the Taliban

https://ift.tt/3sQiXrP Pashtana Durrani knows that she is on the Taliban’s radar. The 23-year-old teacher has been fiercely advocating for girls’ education since the group started making advances in Afghanistan after the U.S. announced it would withdraw troops from the country by Aug. 31 . But despite being told that she is not safe, Durrani is staying put. “I didn’t leave because I just felt like it’s my responsibility to do right by my people,” she says. “This is not just about me. This is about the girls of Afghanistan.” On Aug. 15, the Taliban took control of Afghanistan’s capital 20 years after being ousted from power, triggering a chaotic rush to the Kabul airport as foreign citizens and many Afghans tried to flee the country. Even though the Taliban has promised to respect the rights of women and religious minorities this time, many remain skeptical given its brutal history of oppression. According to Human Rights Watch, schools have been shut down and women have ...

New top story from Time: Supreme Court Delivers Two Major Voting Victories to Democrats. But the Battle May Not Be Over

https://ift.tt/3ea9ynJ The Supreme Court on Wednesday handed Democrats major victories in election legal battles in two critical swing states, letting extended deadlines for mail-in ballots in North Carolina and Pennsylvania remain in place for now. The Supreme Court declined to expedite a decision on Pennsylvania’s extended deadline for receiving mail-in ballots, virtually guaranteeing it will remain in place through the election, and, in a separate ruling, declined to halt an appeals court ruling that kept the North Carolina deadline in place. Justices Samuel Alito, Neil Gorsuch and Clarence Thomas dissented in both of the rulings. The Court’s newest justice, Amy Coney Barrett, who was confirmed on Monday, did not participate because she did not have adequate time to review the filings, according to the court’s public information officer. As a result of the rulings, mail-in ballots postmarked by Election Day can be received through Nov. 6th in Pennsylvania and Nov. 12 ...

New top story from Time: ‘We Not Human At All.’ Why the Fight to Unionize an Alabama Amazon Warehouse Could Spur a Labor Union Resurgence

https://ift.tt/3sGpMvz Darryl Richardson is bone-tired. For a year, he has labored in a sprawling Amazon warehouse in Bessemer, Alabama, collecting the home office supplies, fleece sweatpants, antibacterial wipes and other pandemic purchases that millions of customers have been adding to their virtual shopping carts since the warehouse opened in March 2020. As a “picker” for the retail giant, it is Richardson’s job to gather the items and put them in a tote where they can be sent for packing and shipping. It’s monotonous, labor-intensive work and Richardson says it has taken a physical toll on his 51-year-old body. “I go in there and give it all I can give them,” he says. “My hands be achy, my legs be sore, I be too tired when I get off to do anything. Sometimes I don’t even eat. That’s how tired I be.” But when he’s not working his 10 hour shifts or picking up mandatory overtime hours as a picker, Richardson is taking on a task that is perhaps even more exhausting: chall...

New top story from Time: Blast Outside Kabul Airport Kills 2, Wounds 15, Russia Says

https://ift.tt/3yjY6hU KABUL, Afghanistan — A suicide attack outside Kabul’s airport Thursday killed at least 2 people and wounded 15, Russian officials said. Large crowds of people have massed outside the airport as they try to flee the Taliban takeover of Afghanistan. Western nations had warned earlier in the day of a possible attack at the airport in the waning days of a massive airlift. Suspicion for any attack targeting the crowds would likely fall on the Islamic State group and not the Taliban, who have been deployed at the airport’s gates trying to control the mass of people. [time-brightcove not-tgx=”true”] The Pentagon confirmed the blast, and Russian Foreign Ministry gave the official casualty count. The explosion went off in a crowd of people waiting to enter the airport, according to Adam Khan, an Afghan waiting nearby. He said several people appeared to have been killed or wounded, including some who lost body parts. Several countries urged people to avoid t...

New top story from Time: George Floyd Was ‘Terrified, Scared,’ Says Witness Who Recorded Derek Chauvin Kneeling on His Neck

https://ift.tt/3dcqgTi Darnella Frazier, the teenage witness who took the famous video of George Floyd being crushed into the ground by Minneapolis police officer Derek Chauvin on May 25, 2020, took the stand in Chauvin’s trial on Tuesday and described Floyd as a “man terrified, scared, begging for his life.” Frazier, who was 17 when the incident took place, was not shown on camera and only her voice was heard during her testimony. In the midst of her testimony, Frazier was soft-spoken and at times wept she when she recounted the events of that day. She told the prosecutor that on May 25, she was walking to the Cup Foods grocery store with her 9-year-old cousin to get some snacks. Outside the store, she saw Floyd on the ground with Chauvin on top of him and told her cousin to go inside the store so that the younger child would not see what was happening. “I heard George Floyd saying I can’t breathe, please get off of me. I can’t breathe. He cried for his mom. He was in ...

New top story from Time: The Northwestern U.S. Endures the Hottest Day of an Intense Heat Wave

https://ift.tt/3qzoAK3 SEATTLE — The hottest day of an unprecedented and dangerous heat wave scorched the Pacific Northwest on Monday, with temperatures obliterating records that had been set just the day before. Seattle hit 107 degrees Fahrenheit (42 Celsius) by mid-afternoon — well above Sunday’s all-time high of 104 F (40 C) — on the way to an expected high of 110 F (43 C). Portland, Oregon, reached 115 F (46 C) after hitting new records of 108 F (42 C) on Saturday and 112 F (44 C) on Sunday. The temperatures were unheard of in a region better known for rain, and where June has historically been referred to as “Juneuary” for its cool drizzle. Seattle’s average high temperature in June is around 70 F (21.1 C), and fewer than half of the city’s residents have air conditioning, according to U.S. Census data. [time-brightcove not-tgx=”true”] The heat forced schools and businesses to close to protect workers and guests, including some places like outdoor pools and ice cream...

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