New top story from Time: We Need More Data in the Fight Against Cancer. Here’s a Plan to Help Us Get There

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For the first time in over a year, we are starting to see a light at the end of the tunnel from the devastation caused by COVID-19. While much work remains to end and avoid a resurgence of the pandemic, public and private investments in scientific research will get us to a new normal. The speed to develop, test and manufacture COVID-19 vaccines has shown how science and technology, supported by leadership from governments and the private sector, have the ability to save lives. For example, the CDC’s V-safe program, which recorded side effects, led to the collection of data from tens of millions of people after vaccination, creating a new paradigm for data collection after drug approval.

These successes show just how much can be done when we invest in science and the systems to deploy it effectively. That is why we believe President Biden has the opportunity to lead on another major investment in scientific leadership: the battle to end suffering from cancer.

Despite recent advancements in medicine, cancer still kills more Americans each year than the COVID-19 pandemic has to date. Significant disparities exist, with African-American men having the highest death rates from cancer of any group in the country.

Now in its fifth of seven years, the Cancer Moonshot program, launched under the leadership of then Vice President Biden, has made significant progress. But with challenges remaining, there is a need to renew commitment, refresh priorities and increase funding for Cancer Moonshot 2.0. These efforts will complement and accelerate the National Cancer Institute’s (NCI) existing work.

We see several interrelated priorities for a second Cancer Moonshot, which can unlock new and needed progress in the war on cancer. To begin: standardizing and collecting cancer-patient data (using the same vocabulary to describe medical events and collecting patient data in the same way so they can be compared), especially on outcomes that matter to patients. Patients want to be part of the solution and participate, through use of their privacy-protected data. For too long, electronic health records have been health system–centric, making it difficult for patients, doctors and researchers to track an individual patient’s data over time and across systems. With standardized, patient-centric data, artificial intelligence (AI) can help identify measures for intercepting cancer early, reducing disparities in outcomes and using precision medicine to get treatments to patients who will most benefit from them. With standardized data, we can also create a national cancer data (NatCanDa) repository that researchers can use to inform treatment development, and better pool and share our data with the world. Data holds the clues to better treating cancer.

In addition, we have to modernize systems at the NCI, the FDA, Centers for Medicare and Medicaid Services and other government agencies that collect cancer-related data. Modernized systems, including outcomes, clinical-trial and claims data, will allow us to use real-world evidence to determine which treatments work best for which types of patients and under which models of care, and the most cost-effective ways of delivering those treatments. This will also serve as the foundation of a coordinated cancer clinical trial infrastructure to support faster and more effective drug development.

Together, these initiatives can set up a national “learning health system” for cancer treatment and prevention, where research informs clinical care, and clinical care informs research. Better data sharing and use of real-world evidence can lay the foundation for similar progress on other diseases, especially complex chronic conditions like heart disease and diabetes.

The ability of science to respond to the COVID-19 pandemic shows that, with the right government, scientific, health care, technology and community leadership, we can come together to save lives.

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New top story from Time: The ‘Badass Chief of Staff’ of Turkey’s Opposition Faces Years in Jail After Challenging Erdogan’s Power. She’s Not Backing Down

https://ift.tt/2ZKUTZP Snow brings back memories for Dr. Canan Kaftancioglu. Of recess snowball fights in the Black Sea village where she grew up, of warming her hands at her elementary school’s stove before class — and of discovering a poem by Turkish writer Ataol Behramoglu, a favorite of a beloved uncle who would bring left-wing newspapers to her childhood home and discuss the articles inside. “It is about how the snow brings equality between people,” Kaftancioglu says of the poem. “In the snow, we build a new, more equal world.” The Turkish politician is speaking through an interpreter at her friends’ apartment in Istanbul’s Beyoglu district, seated in an armchair with a beige and brown-spotted dog curled up beside her. In a matter of days or weeks but likely not months, Kaftancioglu expects she will be taken to jail. For now, she’d rather focus on her work: the poverty rate is increasing, and people in her city are suffering. Kaftancioglu represents something unfamil...

New top story from Time: The Documentary Final Account Is a Rare Trove of Unfiltered Interviews With Former Nazis—Too Unfiltered, Some Historians Say

https://ift.tt/3u2CDYI In 2008, documentary filmmaker Luke Holland was looking for a sense of closure. His Viennese maternal grandparents had perished in the Holocaust and, more than six decades later, he wanted to better understand what had happened. So he decided to ask the people who would know: SS members , Wehrmacht fighters, concentration-camp guards and civilian witnesses. “ At first, I embarked on a project with the completely improbable aim of trying to find the people who had killed [my grandparents]. It was quickly clear that I was not going to achieve that,” Holland wrote in a statement about the project. “But I realized I could actually meet their peers. I could meet people who had also raised their arms and their guns for Hitler , people who had committed atrocious crimes. And maybe through them, I might better understand the context in which the Holocaust played out in the heart of a supposedly civilized Europe.” Holland did more than 250 interviews, bu...

New top story from Time: How Spirited Away Changed Animation Forever

https://ift.tt/3xVoGP5 Twenty years ago, on July 20, 2001, a film that would become one of the most celebrated animated movies of all time hit theaters in Japan. Directed by Hayao Miyazaki and produced by Studio Ghibli, Sen to Chihiro no Kamikakushi, titled Spirited Away in English, would leave an indelible mark on animation in the 21st century. The movie arrived at a time when animation was widely perceived as a genre solely for children, and when cultural differences often became barriers to the global distribution of animated works. Spirited Away shattered preconceived notions about the art form and also proved that, as a film created in Japanese with elements of Japanese folklore central to its core, it could resonate deeply with audiences around the world. [time-brightcove not-tgx=”true”] The story follows an ordinary 10-year-old girl, Chihiro, as she arrives at a deserted theme park that turns out to be a realm of gods and spirits. After an overeating incident ...

New top story from Time: Keeping Up with the Kardashians Is Ending. But Their Exploitation of Black Women’s Aesthetics Continues

https://ift.tt/3gahnMY The inaugural episode of Keeping Up with the Kardashians , which debuted on E! in 2007, begins with an irreverent domestic scene. Kim Kardashian , the undisputed protagonist of the show, rummages through the fridge as she’s teased by her family for the size of her posterior. “I think she’s got a little junk in her trunk,” says Kris Jenner, the family’s matriarch and “momager.” She calls her daughter’s butt “jiggly,” as Kim’s sister Khloé Kardashian chimes in from the kitchen table, “Kim’s always had an ass.” [time-brightcove not-tgx=”true”] That the opener of the watershed reality show—which ends June 10 after 20 seasons—centered on the family’s fixation on Kim’s rear foreshadowed the now-ubiquitous public obsession with her body, and particularly that specific feature of it. This outsize fascination was perhaps best embodied by her controversial 2014 Paper magazine cover, shot by Jean-Paul Goude, where her bare bottom is flanked by the line, “Br...

New top story from Time: City Heat is Worse if You’re Not Rich or White. The World’s First Heat Officer Wants to Change That

https://ift.tt/2Us9kTo Jane Gilbert knows she doesn’t get the worst of the sticky heat and humidity that stifles Miami each summer. She lives in Morningside, a coastal suburb of historically preserved art deco and Mediterranean-style single-family homes. Abundant trees shade the streets and a bay breeze cools residents when they leave their air conditioned cars and homes. “I live in a place of privilege and it’s a beautiful area,” says Gilbert, 58, over Zoom in early June, shortly after beginning her job as the world’s first chief heat officer, in Miami Dade county. “But you don’t have to go far to see the disparity.” [time-brightcove not-tgx=”true”] A mile or two inland, in lower income, mostly Black and Latino neighborhoods like Little Haiti, Little Havana and Liberty City, tree cover can be as little as 10%, compared to around 40% in upscale coastal areas, according to Gilbert. Residents wait for buses on unshaded benches. Many can’t afford to buy or run an AC unit. “You ...

FOX NEWS: Man modeled ex-fiancée's wedding dress to try and sell it: Video Sometimes you’ve got to do a little more to snag that sale.

Man modeled ex-fiancée's wedding dress to try and sell it: Video Sometimes you’ve got to do a little more to snag that sale. via FOX NEWS https://ift.tt/3iwCTgo

New top story from Time: We’re in the Third Quarter of the Pandemic. Antarctic Researchers, Mars Simulation Scientists and Navy Submarine Officers Have Advice For How to Get Through It

https://ift.tt/2MtohAV McMurdo Station, an Antarctic research base 2,415 miles south of Christchurch, New Zealand, is a strange place to ride out the COVID-19 pandemic. But it’s been a home of sorts for Pedro Salom since he took a dishwashing job there in 2001, when he was 24. Now an assistant area manager with more than a dozen Antarctic deployments behind him, Salom has grown accustomed to the ebb and flow of life on the ice. There’s the surge of excitement when new arrivals join the camp, the feeling of isolation from the rest of the world when earth and sea disappear in the endless night from April to August; and the joy when the sun finally appears behind the mountains once again. He’s also been around long enough to know that, as people reach the end of their deployments, many begin to struggle—whether they’ve been at McMurdo for over a year, or even just a few months. “One of the things I look for is dramatic changes in people’s habits,” says Salom. “If somebody has...

New top story from Time: China Says It Will Provide COVID-19 Vaccines to Almost 40 African States

https://ift.tt/3f34nYP BEIJING — China said Thursday it is providing COVID-19 vaccines to nearly 40 African countries, describing its actions as purely altruistic in an apparent intensification of what has been described as “vaccine diplomacy.” The vaccines were donated or sold at “favorable prices,” Foreign Ministry official Wu Peng told reporters. Wu compared China’s outreach to the actions of “some countries that have said they have to wait for their own people to finish the vaccination before they could supply the vaccines to foreign countries,” in an apparent dig at the United States. “We believe that it is, of course, necessary to ensure that the Chinese people get vaccinated as soon as possible, but for other countries in need, we also try our best to provide vaccine help,” said Wu, who is director of the ministry’s Africa department. While the U.S. has been accused by some of hoarding vaccines, President Joe Biden on Monday pledged to share an additional 20 mi...

FOX NEWS: Alligator invades Florida post office This gator needs to say later to the post office.

Alligator invades Florida post office This gator needs to say later to the post office. via FOX NEWS https://ift.tt/3gdiGdY

New top story from Time: House Democrats Pass Sweeping Voting Rights Bill Over GOP Opposition

https://ift.tt/3bVXJAY (WASHINGTON) — House Democrats passed sweeping voting and ethics legislation over unanimous Republican opposition, advancing to the Senate what would be the largest overhaul of the U.S. election law in at least a generation. House Resolution 1, which touches on virtually every aspect of the electoral process, was approved Wednesday night on a near party-line 220-210 vote. It would restrict partisan gerrymandering of congressional districts, strike down hurdles to voting and bring transparency to a murky campaign finance system that allows wealthy donors to anonymously bankroll political causes. The bill is a powerful counterweight to voting rights restrictions advancing in Republican-controlled statehouses across the country in the wake of Donald Trump’s repeated false claims of a stolen 2020 election. Yet it faces an uncertain fate in the Democratic-controlled Senate, where it has little chance of passing without changes to procedural rules that curr...

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